Archive for the ‘Allen Frances’ Category

DSM-5 on substance abuse

Monday, August 27th, 2012

Some take the pills; others use the rolled-up twenty to inhale illicit drugs

I'm home and working on my Mac laptop, so I can add a few links and photos to this post. Let's start with a New York Times article dated May 11, 2012 that caused a huge flap. Ian Urbina, a senior NYT reporter is no stranger to controversy, but his article titled, "Addiction Diagnoses May Rise Under Guideline Changes," prompted an unusually strong response from the American Psychiatric Association (APA), the group responsible for revisions to DSM.

Urbina interviewed a number of senior figures in the field and wrote that the new version by expanding the list of associated symptoms in alcohol and drug addiction, adding a new "gambling addiction" diagnosis, and possibly even pasting in an NOS (not otherwise specified) category for "behavioral addiction," could add as many as 20 to 30 million people to those fitting under DSM's umbrella of illnesses.

He quoted Dr. James H. Scully, Jr. the APA's Chief Executive Officer and Medical Director at American Psychiatric Association, as saying "The biggest problem in all of psychiatry is untreated illness and that has huge social (sic) costs."

Others with considerable stature in the mental health (MH) field had qualms. Dr. Allen Frances, head of the DSM-IV revision team, stated , "We'll see false epidemics and medicalization of everyday behavior". Researchers in Australia estimated 60% more people would be considered alcohol addicted under DSM-5's definitions, while a health writer at TIME.com said the new manual could lead to 40% of college students being called alcoholics.

The APA responded with a bit by bit rebuttal of Urbina's article. They noted that DSM-5's terminology would be "substance abuse disorder," not addiction and expected early intervention could stop progression of the problems and therefore benefit society. The diagnosis itself would require more symptoms than in DSM-IV and those would have to produce clinically significant issues. They denied there would be a new NOS behavioral category other than gambling disorder and noted prior DSM versions had a variant of that diagnosis.

Referring back to the 2004 publication of the NESARC study (the National Epidemiologic Survey on Alcohol and Related Conditions) headed by NIH's Dr. Bridget Grant, PhD, PhD (she has a double PhD in psychology and epidemiology), the APA's Work Group noted their recent analysis of her 43,000-subject project  showed no significant change in prevalence. The APA feels it is our healthcare system, not our diagnostic criteria, that determines access to care. The new criteria would include gradations from mild to severe and their take is that this, not the distinction between abuse and dependence, is what is most crucial in improving both prevent and treatment. The APA feels the proposed new health legislation, not the changes to be seen in DSM-5, would expand quantity and quality of therapy.

Others have noted, however, that the APA makes ~$5 million a year from publishing the DSM and APA individual members could profit considerably from the increased number of patients the new guidelines could bring to their practices.

When does the cocktail-hour fan become the twenty-four-hour-a-day drunk?

The July 27, 2012 edition of Psychiatric Times had an article on "Substance Abuse in Aging and Elderly Adults." This arena is often overlooked or forgotten, but as of 2009 the "elderly" made up nearly 13% of the US population and a quarter of all prescription drugs sold in this country go to that group. When data from  a 2009 National Survey on Drug Use and Health performed by SAMHSA, the Substance Abuse and Mental Health Services Administration, were examined, there were marked increases in illicit drug use in older adults. For those over 50, alcohol is the most common substance abused, but opiates were the second ,while anti-anxiety drugs and skeletal muscle relaxants were also  on the commonly misused list.

The bottom line, I think, is that substance abuse is common, seen at all ages from youth to the elderly, and a significant problem in this country. There is considerable debate, even among experts in the field as to what criteria should be applied in diagnosing this problem and Dr, Allen's comments on the APA's role in crafting DSM should be taken seriously.

DSM-comments and critiques: part 2

Sunday, August 19th, 2012

I'm still traveling, but back in the swing of writing posts on the numerous changes to DSM-5 the Diagnostic and Statistical Manual of Mental Disorders, that is supposed to be published (finally) in May of 2013. I've been reading background material, papers with advance critiques and older criteria for some of the diagnoses.

I still can't add photos as I'll be using my iPad until I get home four days from now, so I'll give you a URL or two and some titles you can Google.

I'll start with mentioning a long, multi-part fascinating paper that is appearing in 'Philosophy, Ethics and Humanities in Medicine'. It's called "The six most essential questions in psychiatric diagnosis: a pleuralogue."  The second author, Allen Frances, a Duke School of Medicine Emeritus Professor of Psychiatry, was the leader of the group that put together DSM-IV. I'll come back to these articles in a later post, but used the first one to find short commentaries on DSM-5.

The lead author, Dr. James Phillips, is an Associate Clinical Professor of Psychiatry at Yale. In November, 2011 he wrote an article for 'Psychiatric Times,' titled "The Great DSM-5 Personality Bazaar," and in March of 2012, in the same publication, a piece titled "DSM-5 In the Homestretch--1. Integrating the Coding Systems."

That first piece told of diagnoses, e.g., narcissistic personality disorder, that were excluded in drafts of the new manual and later re-included. The total number of Personality Disorders ended up at six, down from ten, at the time Dr. Phillips wrote his commentary.

One category that was removed was Paranoid Personality Disorder. It seemed worthy of inclusion to Phillips, certainly as much so as another that was kept. Personality Disorder NOS (not otherwise specified), was apparently changed to Personality Disorder Trait Specified (PDTS), which to me at least is a potentially confusing acronym. There is PTSD after all, a term most of us have some familiarity with.

Dr. Mark Zimmerman et al. published a study of 2,150 psychiatric outpatients (you  can find it at www.ncbi.nim.nih.gov/pubmed/21903031) which said that DSM-IV's method, using three trait categories: absent, sub threshold or present, was just as effective as the proposed diagnostic approach of DSM-5.

Dr. Phillips, in his later article, mentioned coding, how to relate the International Classification of Diseases (ICD) with the DSM, often for billing purposes. Our country has a treaty obligation to use the ICD and at present is using a "clinical modification" of the 1978 ICD-9 version. Some diagnoses used by US mental health (MH) therapists aren't in the ICD at all and the new American version of the international coding system, ICD-10CM, originally supposed to be available in October 2013, has been delayed. Of course the rest of the world already uses ICD-10.

Dr Frances in an April 25, 2012 piece in the New York Times, "Diagnosing the DSM-5: Shrink Revolt," was said to be opposed to the first draft of the new version as being too promiscuous with its diagnostic labels. He cites the proposed Binge Eating Disorder which may be present in 6% of the total US population (using the proposed definition).

He then commented, "And that is before the drug companies start marketing something for it."

He had similar reservations about three other tentative new DSM labels: one could be applied to kids with "typical temper problems;" another to anyone who has lost a spouse and is grief-stricken for two weeks. The third, "Psychosis Risk Syndrome," in his opinion, could misidentify many youngsters and treat others with anti-psychotic meds without any evidence that such early treatment is helpful.

By the May, 2012 meeting of the American Psychiatric Association (APA), two of those four problematic categories had been discarded. Dr Francis was still not content and published a NYT Op-Ed piece on May 11th titled "Diagnosing the D.S.M.," which said it's time to open the DSM's revision to all the MH disciplines as well to the primary care doctors who prescribe most of the drugs used for MH disorders.